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Reasons for exclusion: Key Question 1 (n = 1,192*) Exclusion Code Exclusion Reason Count X-1 Does not embody an intervention or treatment for uterine fibroids 555 Basic science (X-1a) Genetics/etiology (X-1b) Imaging/analysis (X-1c) Pathophysiology/physiology (X-1d) Pre-operative adjuncts to shrink fibroids or enhance anemia (X-1e) Risk elements (X-1f) Case report (X-1g) Other (X-1h) Not uterine fibroid (X-1i) X-2 Not unique research 548 X-three Not an eligible research design 493 Prospective or retrospective cohort research (X-3a) Non-randomized trial (X-3b) Case sequence (X-3c) Case report (X-3d) Case-management (X-3e) Other (X-3f) X-four Not carried out in an eligible nation 36 X-5 Population isn't ladies with uterine fibroids or doesn't report knowledge individually from 54 blended population X-6 Does not report an outcome of curiosity 112 X-7 Does not tackle a Key Question 162 X-10 Unavailable 1 X-11 Non-English 107 X-12 Duplicate 6 *Total rely exceeds number of data as records can be excluded for more than one cause 1. 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